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Re-evaluation of the roles of DROSHA, Exportin 5, and DICER in microRNA biogenesis

Biogenesis of canonical microRNAs (miRNAs) involves multiple steps: nuclear processing of primary miRNA (pri-miRNA) by DROSHA, nuclear export of precursor miRNA (pre-miRNA) by Exportin 5 (XPO5), and cytoplasmic processing of pre-miRNA by DICER. To gain a deeper understanding of the contribution of e...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Kim, Young-Kook, Kim, Boseon, Kim, V. Narry
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822641/
https://ncbi.nlm.nih.gov/pubmed/26976605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602532113
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