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An Exportin-1–dependent microRNA biogenesis pathway during human cell quiescence

The reversible state of proliferative arrest known as “cellular quiescence” plays an important role in tissue homeostasis and stem cell biology. By analyzing the expression of miRNAs and miRNA-processing factors during quiescence in primary human fibroblasts, we identified a group of miRNAs that are...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Martinez, Ivan, Hayes, Karen E., Barr, Jamie A., Harold, Abby D., Xie, Mingyi, Bukhari, Syed I. A., Vasudevan, Shobha, Steitz, Joan A., DiMaio, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488920/
https://ncbi.nlm.nih.gov/pubmed/28584122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618732114
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