Neonatal rhinovirus infection induces mucous metaplasia and airways hyperresponsiveness

Recent studies link early rhinovirus (RV) infections to later asthma development. We hypothesized that neonatal RV infection leads to an IL-13-driven asthma-like phenotype in mice. BALB/c mice were inoculated with RV1B or sham on day 7 of life. Viral RNA persisted in the neonatal lung up to 7 days a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schneider, Dina, Hong, Jun Y., Popova, Antonia P., Bowman, Emily R., Linn, Marisa J., McLean, Alan M., Zhao, Ying, Sonstein, Joanne, Bentley, J. Kelley, Weinberg, Jason B., Lukacs, Nicholas W., Curtis, Jeffrey L., Sajjan, Uma S., Hershenson, Marc B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294163/
https://ncbi.nlm.nih.gov/pubmed/22331068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101391
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados