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Neonatal rhinovirus infection induces mucous metaplasia and airways hyperresponsiveness
Recent studies link early rhinovirus (RV) infections to later asthma development. We hypothesized that neonatal RV infection leads to an IL-13-driven asthma-like phenotype in mice. BALB/c mice were inoculated with RV1B or sham on day 7 of life. Viral RNA persisted in the neonatal lung up to 7 days a...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294163/ https://ncbi.nlm.nih.gov/pubmed/22331068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101391 |
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