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Targeted Disruption of Ephrin B1 in Cells of Myeloid Lineage Increases Osteoclast Differentiation and Bone Resorption in Mice

Disruption of ephrin B1 in collagen I producing cells in mice results in severe skull defects and reduced bone formation. Because ephrin B1 is also expressed during osteoclast differentiation and because little is known on the role of ephrin B1 reverse signaling in bone resorption, we examined the b...

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Autors principals: Cheng, Shaohong, Zhao, Shien Lucy, Nelson, Brittany, Kesavan, Chandrasekhar, Qin, Xuezhong, Wergedal, Jon, Mohan, Subburaman, Xing, Weirong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293909/
https://ncbi.nlm.nih.gov/pubmed/22403721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032887
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