Загрузка...
Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading
To establish a causal role for locally produced IGF-I in the mechanical strain response in the bone, we have generated mice with conditional disruption of the insulin-like growth factor (IGF) I gene in type 1α(2) collagen-expressing cells using the Cre-loxP approach. At 10 wk of age, loads adjusted...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2011
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233773/ https://ncbi.nlm.nih.gov/pubmed/21878662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00440.2011 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|