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Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation

Claudin 18 (Cldn-18) belongs to a large family of transmembrane proteins that are important components of tight junction strands. Although several claudin members are expressed in bone, the functional role for any claudin member in bone is unknown. Here we demonstrate that disruption of Cldn-18 in m...

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Detalhes bibliográficos
Main Authors: Linares, Gabriel R., Brommage, Robert, Powell, David R., Xing, Weirong, Chen, Shin-Tai, Alshbool, Fatima Z., Lau, KH William, Wergedal, Jon E., Mohan, Subburaman
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377820/
https://ncbi.nlm.nih.gov/pubmed/22437732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1600
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