DJ-1 Null Dopaminergic Neuronal Cells Exhibit Defects in Mitochondrial Function and Structure: Involvement of Mitochondrial Complex I Assembly

DJ-1 is a Parkinson's disease-associated gene whose protein product has a protective role in cellular homeostasis by removing cytosolic reactive oxygen species and maintaining mitochondrial function. However, it is not clear how DJ-1 regulates mitochondrial function and why mitochondrial dysfun...

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Detalhes bibliográficos
Main Authors: Heo, Jun Young, Park, Ji Hoon, Kim, Soung Jung, Seo, Kang Sik, Han, Jeong Su, Lee, Sang Hee, Kim, Jin Man, Park, Jong Il, Park, Seung Kiel, Lim, Kyu, Hwang, Byung Doo, Shong, Minho, Kweon, Gi Ryang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293835/
https://ncbi.nlm.nih.gov/pubmed/22403686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032629
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