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p15(INK4b) plays a crucial role in murine lymphoid development and tumorigenesis
To investigate if the cooperation between the Rgr oncogene and the inactivation of INK4b (a CDK inhibitor), as described previously in a sarcoma model, would be operational in a lymphoid system in vivo, we generated a transgenic/knockout murine model. Transgenic mice expressing the Rgr oncogene unde...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3291865/ https://ncbi.nlm.nih.gov/pubmed/22227036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs003 |
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