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p15(INK4b) plays a crucial role in murine lymphoid development and tumorigenesis

To investigate if the cooperation between the Rgr oncogene and the inactivation of INK4b (a CDK inhibitor), as described previously in a sarcoma model, would be operational in a lymphoid system in vivo, we generated a transgenic/knockout murine model. Transgenic mice expressing the Rgr oncogene unde...

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Hlavní autoři: Osei-Sarfo, Kwame, Perez de Castro, Ignacio, Pellicer, Angel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291865/
https://ncbi.nlm.nih.gov/pubmed/22227036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs003
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