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p38MAPK plays a crucial role in stromal mediated tumorigenesis

Neoplastic cells rely on the tumor microenvironment (TME) for survival and progression factors. Indeed, senescent and cancer-associated fibroblasts (CAFs) express factors that promote tumorigenesis that are collectively referred to as the senescence-associated secretory phenotype (SASP). Despite the...

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Bibliografische gegevens
Hoofdauteurs: Alspach, Elise, Flanagan, Kevin C., Luo, Xianmin, Ruhland, Megan K., Huang, Hui, Pazolli, Ermira, Donlin, Maureen J., Marsh, Timothy, Piwnica-Worms, David, Monahan, Joseph, Novack, Deborah V., McAllister, Sandra S., Stewart, Sheila A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049323/
https://ncbi.nlm.nih.gov/pubmed/24670723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0743
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