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Osteopontin Stimulates Preneoplastic Cellular Proliferation Through Activation of the MAPK Pathway
Alterations in the microenvironment collaborate with cell autonomous mutations during the transformation process. Indeed, cancer- associated fibroblasts (CAF) and senescent fibroblasts stimulate tumorigenesis in xenograft models. Because senescent fibroblasts accumulate with age, these findings sugg...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685505/ https://ncbi.nlm.nih.gov/pubmed/21673011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0472 |
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