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UCP2 Modulates Cell Proliferation through the MAPK/ERK Pathway during Erythropoiesis and Has No Effect on Heme Biosynthesis

UCP2, an inner membrane mitochondrial protein, has been implicated in bioenergetics and reactive oxygen species (ROS) modulation. High levels of UCP2 mRNA were recently found in erythroid cells where UCP2 is hypothesized to function as a facilitator of heme synthesis and iron metabolism by reducing...

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Bibliografski detalji
Glavni autori: Elorza, Alvaro, Hyde, Brigham, Mikkola, Hanna K., Collins, Sheila, Shirihai, Orian S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576537/
https://ncbi.nlm.nih.gov/pubmed/18687678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805400200
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