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The mitochondrial uncoupling protein 2 (UCP2) inhibits mast cell activation and reduces histamine content

Mast cells are immune effector cells that are involved in allergies and inflammation through the release of mediators such as histamine, prostaglandins and cytokines. Uncoupling protein 2 (UCP2) is a mitochondrial protein that inhibits insulin secretion from β-cells, possibly through downregulation...

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Detalhes bibliográficos
Main Authors: Tagen, Michael, Elorza, Alvaro, Kempuraj, Duraisamy, Boucher, William, Kepley, Christopher L., Shirihai, Orian S., Theoharides, Theoharis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925218/
https://ncbi.nlm.nih.gov/pubmed/19846869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803422
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