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The mitochondrial uncoupling protein 2 (UCP2) inhibits mast cell activation and reduces histamine content

Mast cells are immune effector cells that are involved in allergies and inflammation through the release of mediators such as histamine, prostaglandins and cytokines. Uncoupling protein 2 (UCP2) is a mitochondrial protein that inhibits insulin secretion from β-cells, possibly through downregulation...

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Autors principals: Tagen, Michael, Elorza, Alvaro, Kempuraj, Duraisamy, Boucher, William, Kepley, Christopher L., Shirihai, Orian S., Theoharides, Theoharis C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925218/
https://ncbi.nlm.nih.gov/pubmed/19846869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803422
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