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The mitochondrial uncoupling protein 2 (UCP2) inhibits mast cell activation and reduces histamine content

Mast cells are immune effector cells that are involved in allergies and inflammation through the release of mediators such as histamine, prostaglandins and cytokines. Uncoupling protein 2 (UCP2) is a mitochondrial protein that inhibits insulin secretion from β-cells, possibly through downregulation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tagen, Michael, Elorza, Alvaro, Kempuraj, Duraisamy, Boucher, William, Kepley, Christopher L., Shirihai, Orian S., Theoharides, Theoharis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925218/
https://ncbi.nlm.nih.gov/pubmed/19846869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803422
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