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Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks
DNA double-strand breaks (DSBs) are the most deleterious lesion inflicted by ionizing radiation. Although DSBs are potentially carcinogenic, it is not clear whether complex DSBs that are refractory to repair are more potently tumorigenic compared with simple breaks that can be rapidly repaired, corr...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950935/ https://ncbi.nlm.nih.gov/pubmed/20663777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq153 |
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