Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks

DNA double-strand breaks (DSBs) are the most deleterious lesion inflicted by ionizing radiation. Although DSBs are potentially carcinogenic, it is not clear whether complex DSBs that are refractory to repair are more potently tumorigenic compared with simple breaks that can be rapidly repaired, corr...

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Detalhes bibliográficos
Main Authors: Camacho, Cristel V., Mukherjee, Bipasha, McEllin, Brian, Ding, Liang-Hao, Hu, Burong, Habib, Amyn A., Xie, Xian-Jin, Nirodi, Chaitanya S., Saha, Debabrata, Story, Michael D., Balajee, Adayabalam S., Bachoo, Robert M., Boothman, David A., Burma, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950935/
https://ncbi.nlm.nih.gov/pubmed/20663777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq153
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