PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo

Defective Fas signaling leads to resistance to various anticancer therapies. Presence of potential inhibitors of Fas which could block Fas signaling can explain cancer cells resistance to apoptosis. We identified promyelocytic leukemia protein (PML) as a Fas-interacting protein using mass spectromet...

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Detalhes bibliográficos
Main Authors: Tao, Rong-Hua, Berkova, Zuzana, Wise, Jillian F., Rezaeian, Abdol-Hossein, Daniluk, Urszula, Ao, Xue, Hawke, David H., Karp, Judith E., Lin, Hui-Kuan, Molldrem, Jeffrey J., Samaniego, Felipe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291494/
https://ncbi.nlm.nih.gov/pubmed/21803845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-349670
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