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Endocrine fibroblast growth factors 15/19 and 21: from feast to famine
We review the physiology and pharmacology of two atypical fibroblast growth factors (FGFs)—FGF15/19 and FGF21—that can function as hormones. Both FGF15/19 and FGF21 act on multiple tissues to coordinate carbohydrate and lipid metabolism in response to nutritional status. Whereas FGF15/19 is secreted...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289879/ https://ncbi.nlm.nih.gov/pubmed/22302876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.184788.111 |
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