Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

Although loss of epithelial integrity is a hallmark of advanced cancer, it remains poorly understood whether genetic alterations corrupting this integrity causally facilitate tumorigenesis. We show that conditional deletion of tumor suppressor gene Lkb1 (Par-4) in the mammary gland compromises epith...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Partanen, Johanna I., Tervonen, Topi A., Myllynen, Mikko, Lind, Essi, Imai, Misa, Katajisto, Pekka, Dijkgraaf, Gerrit J. P., Kovanen, Panu E., Mäkelä, Tomi P., Werb, Zena, Klefström, Juha
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289385/
https://ncbi.nlm.nih.gov/pubmed/22308451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120421109
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller