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Amphotericin primarily kills yeast by simply binding ergosterol
Amphotericin B (AmB) is a prototypical small molecule natural product that can form ion channels in living eukaryotic cells and has remained refractory to microbial resistance despite extensive clinical utilization in the treatment of life-threatening fungal infections for more than half a century....
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289339/ https://ncbi.nlm.nih.gov/pubmed/22308411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117280109 |
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