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Disruption of Ergosterol Biosynthesis Confers Resistance to Amphotericin B in Candida lusitaniae

Candida lusitaniae is an emerging human pathogen that, unlike other fungal pathogens, frequently develops resistance to the commonly used antifungal agent amphotericin B. Amphotericin B is a member of the polyene class of antifungal drugs, which impair fungal cell membrane integrity. Here we analyze...

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Detalhes bibliográficos
Main Authors: Young, Laura Y., Hull, Christina M., Heitman, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC182600/
https://ncbi.nlm.nih.gov/pubmed/12936965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2717-2724.2003
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