Disruption of Ergosterol Biosynthesis Confers Resistance to Amphotericin B in Candida lusitaniae

Candida lusitaniae is an emerging human pathogen that, unlike other fungal pathogens, frequently develops resistance to the commonly used antifungal agent amphotericin B. Amphotericin B is a member of the polyene class of antifungal drugs, which impair fungal cell membrane integrity. Here we analyze...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Young, Laura Y., Hull, Christina M., Heitman, Joseph
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2717-2724.2003
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