A carregar...
The C2′–OH of Amphotericin B Plays an Important Role in Binding the Primary Sterol of Human But Not Yeast Cells
Amphotericin B (AmB) is a clinically vital anti-mycotic but is limited by its severe toxicity. Binding ergosterol, independent of channel formation, is the primary mechanism by which AmB kills yeast, and binding cholesterol may primarily account for toxicity to human cells. The leading structural mo...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753100/ https://ncbi.nlm.nih.gov/pubmed/23718627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja403255s |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|