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Amphotericin primarily kills yeast by simply binding ergosterol

Amphotericin B (AmB) is a prototypical small molecule natural product that can form ion channels in living eukaryotic cells and has remained refractory to microbial resistance despite extensive clinical utilization in the treatment of life-threatening fungal infections for more than half a century....

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Detalhes bibliográficos
Main Authors: Gray, Kaitlyn C., Palacios, Daniel S., Dailey, Ian, Endo, Matthew M., Uno, Brice E., Wilcock, Brandon C., Burke, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289339/
https://ncbi.nlm.nih.gov/pubmed/22308411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117280109
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