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A DNA binding domain is contained in the C-terminus of wild type p53 protein.
In the present study we evaluated the DNA binding activity of wild type and mutant p53 proteins that were isolated from bacterial expression vectors. A comparison of the binding activities of the various purified p53 proteins, assessed by their ability to bind DNA cellulose columns, indicated that w...
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| Pubblicato in: | Nucleic Acids Res |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1991
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1923804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.19.5191 |
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