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A DNA binding domain is contained in the C-terminus of wild type p53 protein.

In the present study we evaluated the DNA binding activity of wild type and mutant p53 proteins that were isolated from bacterial expression vectors. A comparison of the binding activities of the various purified p53 proteins, assessed by their ability to bind DNA cellulose columns, indicated that w...

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Bibliografiske detaljer
Main Authors: Foord, O S, Bhattacharya, P, Reich, Z, Rotter, V
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC328875/
https://ncbi.nlm.nih.gov/pubmed/1923804
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