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Antinociceptive Effects of Herkinorin, a MOP Receptor Agonist Derived from Salvinorin A in the Formalin Test in Rats: New Concepts in Mu Opioid Receptor Pharmacology()

Herkinorin is the first μ opioid (MOP) selective agonist derived from salvinorin A, a hallucinogenic natural product. Previous work has shown that, unlike other opioids, herkinorin does not promote the recruitment of β-arrestin-2 to the MOP receptor and does not lead to receptor internalization. Thi...

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Hlavní autoři: Lamb, Kenneth, Tidgewell, Kevin, Simpson, Denise S., Bohn, Laura M., Prisinzano, Thomas E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288203/
https://ncbi.nlm.nih.gov/pubmed/22119134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2011.10.026
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