An Opioid Agonist that Does Not Induce μ-Opioid Receptor—Arrestin Interactions or Receptor Internalization

G protein-coupled receptor desensitization and trafficking are important regulators of opioid receptor signaling that can dictate overall drug responsiveness in vivo. Furthermore, different μ-opioid receptor (μOR) ligands can lead to varying degrees of receptor regulation, presumably because of dist...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Groer, C. E., Tidgewell, K., Moyer, R. A., Harding, W. W., Rothman, R. B., Prisinzano, T. E., Bohn, L. M.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926195/
https://ncbi.nlm.nih.gov/pubmed/17090705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.106.028258
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