The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults. Long-term survival of patients with AML has changed little over the past decade, necessitating the identification and validation of new AML targets. Integration of genomic approaches with small-molecule and genetically...

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Main Authors: Banerji, Versha, Frumm, Stacey M., Ross, Kenneth N., Li, Loretta S., Schinzel, Anna C., Hahn, Cynthia K., Kakoza, Rose M., Chow, Kwan T., Ross, Linda, Alexe, Gabriela, Tolliday, Nicola, Inguilizian, Haig, Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Roti, Giovanni, Aster, Jon C., Hahn, William C., Kung, Andrew L., Stegmaier, Kimberly
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287215/
https://ncbi.nlm.nih.gov/pubmed/22326953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46465
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