The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults. Long-term survival of patients with AML has changed little over the past decade, necessitating the identification and validation of new AML targets. Integration of genomic approaches with small-molecule and genetically...

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Autores principales: Banerji, Versha, Frumm, Stacey M., Ross, Kenneth N., Li, Loretta S., Schinzel, Anna C., Hahn, Cynthia K., Kakoza, Rose M., Chow, Kwan T., Ross, Linda, Alexe, Gabriela, Tolliday, Nicola, Inguilizian, Haig, Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Roti, Giovanni, Aster, Jon C., Hahn, William C., Kung, Andrew L., Stegmaier, Kimberly
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287215/
https://ncbi.nlm.nih.gov/pubmed/22326953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46465
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