The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults. Long-term survival of patients with AML has changed little over the past decade, necessitating the identification and validation of new AML targets. Integration of genomic approaches with small-molecule and genetically...

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Main Authors: Banerji, Versha, Frumm, Stacey M., Ross, Kenneth N., Li, Loretta S., Schinzel, Anna C., Hahn, Cynthia K., Kakoza, Rose M., Chow, Kwan T., Ross, Linda, Alexe, Gabriela, Tolliday, Nicola, Inguilizian, Haig, Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Roti, Giovanni, Aster, Jon C., Hahn, William C., Kung, Andrew L., Stegmaier, Kimberly
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287215/
https://ncbi.nlm.nih.gov/pubmed/22326953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46465
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