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Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability
Microsatellite DNA synthesis represents a significant component of human genome replication that must occur faithfully. However, yeast replicative DNA polymerases do not possess high fidelity for microsatellite synthesis. We hypothesized that the structural features of Y-family polymerases that faci...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287198/ https://ncbi.nlm.nih.gov/pubmed/22021378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr889 |
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