REV1 restrains DNA polymerase ζ to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo

Exposure to ultraviolet light induces a number of forms of damage in DNA, of which (6–4) photoproducts present the most formidable challenge to DNA replication. No single DNA polymerase has been shown to bypass these lesions efficiently in vitro suggesting that the coordinate use of a number of diff...

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Main Authors: Szüts, Dávid, Marcus, Adam P., Himoto, Masayuki, Iwai, Shigenori, Sale, Julian E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588525/
https://ncbi.nlm.nih.gov/pubmed/18953031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn651
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