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Integrin α(6)β(4) cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation
The α(6)β(4) integrin promotes carcinoma invasion through its ability to promote directed migration and polarization of carcinoma cells. In this study, we explore how the α(6)β(4) integrin cooperates with lysophosphatidic acid (LPA) to activate Rho and Rac small GTPases. Through the use of dominant...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287157/ https://ncbi.nlm.nih.gov/pubmed/22049212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00095.2011 |
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