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Integrin α(6)β(4) cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation
The α(6)β(4) integrin promotes carcinoma invasion through its ability to promote directed migration and polarization of carcinoma cells. In this study, we explore how the α(6)β(4) integrin cooperates with lysophosphatidic acid (LPA) to activate Rho and Rac small GTPases. Through the use of dominant...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287157/ https://ncbi.nlm.nih.gov/pubmed/22049212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00095.2011 |
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