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Integrin α(6)β(4) cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation

The α(6)β(4) integrin promotes carcinoma invasion through its ability to promote directed migration and polarization of carcinoma cells. In this study, we explore how the α(6)β(4) integrin cooperates with lysophosphatidic acid (LPA) to activate Rho and Rac small GTPases. Through the use of dominant...

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書誌詳細
主要な著者: O'Connor, Kathleen L., Chen, Min, Towers, L. Nicole
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287157/
https://ncbi.nlm.nih.gov/pubmed/22049212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00095.2011
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