Subtype and pathway specific responses to anticancer compounds in breast cancer

Breast cancers are comprised of molecularly distinct subtypes that may respond differently to pathway-targeted therapies now under development. Collections of breast cancer cell lines mirror many of the molecular subtypes and pathways found in tumors, suggesting that treatment of cell lines with can...

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Bibliographic Details
Main Authors: Heiser, Laura M., Sadanandam, Anguraj, Kuo, Wen-Lin, Benz, Stephen C., Goldstein, Theodore C., Ng, Sam, Gibb, William J., Wang, Nicholas J., Ziyad, Safiyyah, Tong, Frances, Bayani, Nora, Hu, Zhi, Billig, Jessica I., Dueregger, Andrea, Lewis, Sophia, Jakkula, Lakshmi, Korkola, James E., Durinck, Steffen, Pepin, François, Guan, Yinghui, Purdom, Elizabeth, Neuvial, Pierre, Bengtsson, Henrik, Wood, Kenneth W., Smith, Peter G., Vassilev, Lyubomir T., Hennessy, Bryan T., Greshock, Joel, Bachman, Kurtis E., Hardwicke, Mary Ann, Park, John W., Marton, Laurence J., Wolf, Denise M., Collisson, Eric A., Neve, Richard M., Mills, Gordon B., Speed, Terence P., Feiler, Heidi S., Wooster, Richard F., Haussler, David, Stuart, Joshua M., Gray, Joe W., Spellman, Paul T.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Breast Cancer Special Feature
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286973/
https://ncbi.nlm.nih.gov/pubmed/22003129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018854108
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