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Subtype and pathway specific responses to anticancer compounds in breast cancer

Breast cancers are comprised of molecularly distinct subtypes that may respond differently to pathway-targeted therapies now under development. Collections of breast cancer cell lines mirror many of the molecular subtypes and pathways found in tumors, suggesting that treatment of cell lines with can...

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Detalhes bibliográficos
Main Authors: Heiser, Laura M., Sadanandam, Anguraj, Kuo, Wen-Lin, Benz, Stephen C., Goldstein, Theodore C., Ng, Sam, Gibb, William J., Wang, Nicholas J., Ziyad, Safiyyah, Tong, Frances, Bayani, Nora, Hu, Zhi, Billig, Jessica I., Dueregger, Andrea, Lewis, Sophia, Jakkula, Lakshmi, Korkola, James E., Durinck, Steffen, Pepin, François, Guan, Yinghui, Purdom, Elizabeth, Neuvial, Pierre, Bengtsson, Henrik, Wood, Kenneth W., Smith, Peter G., Vassilev, Lyubomir T., Hennessy, Bryan T., Greshock, Joel, Bachman, Kurtis E., Hardwicke, Mary Ann, Park, John W., Marton, Laurence J., Wolf, Denise M., Collisson, Eric A., Neve, Richard M., Mills, Gordon B., Speed, Terence P., Feiler, Heidi S., Wooster, Richard F., Haussler, David, Stuart, Joshua M., Gray, Joe W., Spellman, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286973/
https://ncbi.nlm.nih.gov/pubmed/22003129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018854108
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