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Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2

With interest waning in the use of cyclooxygenase-2 (COX-2) inhibitors for inflammatory disease, prostaglandin receptors provide alternative targets for the treatment of COX-2–mediated pathological conditions in both the periphery and the central nervous system. Activation of prostaglandin E2 recept...

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Detalhes bibliográficos
Main Authors: Jiang, Jianxiong, Ganesh, Thota, Du, Yuhong, Quan, Yi, Serrano, Geidy, Qui, Min, Speigel, Iris, Rojas, Asheebo, Lelutiu, Nadia, Dingledine, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286971/
https://ncbi.nlm.nih.gov/pubmed/22323596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120195109
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