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Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily of signaling molecules. BMPs can elicit a wide range of effects in many cell types and have previously been shown to induce growth inhibition in carcinoma cells as well as normal epithelia. Recently, it has been demonstrated tha...

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Autori principali: Owens, Philip, Pickup, Michael W., Novitskiy, Sergey V., Chytil, Anna, Gorska, Agnieszka E., Aakre, Mary E., West, James, Moses, Harold L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286911/
https://ncbi.nlm.nih.gov/pubmed/21576484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101139108
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