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Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily of signaling molecules. BMPs can elicit a wide range of effects in many cell types and have previously been shown to induce growth inhibition in carcinoma cells as well as normal epithelia. Recently, it has been demonstrated tha...

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Autores principales: Owens, Philip, Pickup, Michael W., Novitskiy, Sergey V., Chytil, Anna, Gorska, Agnieszka E., Aakre, Mary E., West, James, Moses, Harold L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286911/
https://ncbi.nlm.nih.gov/pubmed/21576484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101139108
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