Up-regulation of Cavβ(3) Subunit in Primary Sensory Neurons Increases Voltage-activated Ca(2+) Channel Activity and Nociceptive Input in Neuropathic Pain

High voltage-activated calcium channels (HVACCs) are essential for synaptic and nociceptive transmission. Although blocking HVACCs can effectively reduce pain, this treatment strategy is associated with intolerable adverse effects. Neuronal HVACCs are typically composed of α(1), β (Cavβ), and α(2)δ...

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Detaylı Bibliyografya
Asıl Yazarlar: Li(李, Li, 莉), Cao(红, Xue-Hong, 曹雪), Chen(瑞, Shao-Rui, 陈少), Han(동, Hee-Dong, 한희), Lopez-Berestein, Gabriel, Sood, Anil K., Pan(麟, Hui-Lin, 潘惠)
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Neurobiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285367/
https://ncbi.nlm.nih.gov/pubmed/22187436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.310110
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