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Up-regulation of Cavβ(3) Subunit in Primary Sensory Neurons Increases Voltage-activated Ca(2+) Channel Activity and Nociceptive Input in Neuropathic Pain
High voltage-activated calcium channels (HVACCs) are essential for synaptic and nociceptive transmission. Although blocking HVACCs can effectively reduce pain, this treatment strategy is associated with intolerable adverse effects. Neuronal HVACCs are typically composed of α(1), β (Cavβ), and α(2)δ...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285367/ https://ncbi.nlm.nih.gov/pubmed/22187436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.310110 |
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