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Contribution of Phosphates and Adenine to the Potency of Adenophostins at the IP(3) Receptor: Synthesis of All Possible Bisphosphates of Adenophostin A
[Image: see text] Although adenophostin A (AdA), the most potent agonist of d-myo-inositol 1,4,5-trisphosphate receptors (IP(3)R), is thought to mimic IP(3), the relative roles of the different phosphate groups and the adenosine motif have not been established. We synthesized all three possible bisp...
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| Główni autorzy: | , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2012
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285137/ https://ncbi.nlm.nih.gov/pubmed/22248345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201571p |
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