Stimulation of Inositol 1,4,5-Trisphosphate (IP(3)) Receptor Subtypes by Adenophostin A and Its Analogues

Inositol 1,4,5-trisphosphate receptors (IP(3)R) are intracellular Ca(2+) channels. Most animal cells express mixtures of the three IP(3)R subtypes encoded by vertebrate genomes. Adenophostin A (AdA) is the most potent naturally occurring agonist of IP(3)R and it shares with IP(3) the essential featu...

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Bibliographic Details
Main Authors: Saleem, Huma, Tovey, Stephen C., Riley, Andrew M., Potter, Barry V. L., Taylor, Colin W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585173/
https://ncbi.nlm.nih.gov/pubmed/23469136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058027
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