Interactions of antagonists with subtypes of inositol 1,4,5-trisphosphate (IP(3)) receptor

BACKGROUND AND PURPOSE: Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are intracellular Ca(2+) channels. Interactions of the commonly used antagonists of IP(3)Rs with IP(3)R subtypes are poorly understood. EXPERIMENTAL APPROACH: IP(3)-evoked Ca(2+) release from permeabilized DT40 cells stably exp...

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Autors principals: Saleem, Huma, Tovey, Stephen C, Molinski, Tedeusz F, Taylor, Colin W
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080982/
https://ncbi.nlm.nih.gov/pubmed/24628114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12685
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