Determinants of adenophostin A binding to inositol trisphosphate receptors.

Inositol 1,4,5-trisphosphate (IP(3)) receptors from cerebellum and recombinant type 1 IP(3) receptors expressed in Sf9 cells had indistinguishable affinities for IP(3) ( K (d)=6.40+/-0.48 nM) and adenophostin A ( K (d)=0.89+/-0.05 nM). In cytosol-like medium, each of the three mammalian IP(3) recept...

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Main Authors: Morris, Stephen A, Nerou, Edmund P, Riley, Andrew M, Potter, Barry V L, Taylor, Colin W
格式: Artigo
語言:Inglês
出版: 2002
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222864/
https://ncbi.nlm.nih.gov/pubmed/12088506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020675
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