Rapid activation and partial inactivation of inositol trisphosphate receptors by adenophostin A.

Adenophostin A, the most potent known agonist of inositol 1,4, 5-trisphosphate (InsP(3)) receptors, stimulated (45)Ca(2+) release from the intracellular stores of permeabilized hepatocytes. The concentration of adenophostin A causing the half-maximal effect (EC(50)) was 7.1+/-0.5 nM, whereas the EC(...

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Bibliografski detalji
Glavni autori: Adkins, C E, Wissing, F, Potter, B V, Taylor, C W
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221536/
https://ncbi.nlm.nih.gov/pubmed/11104705
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