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Inositol Adenophostin: Convergent Synthesis of a Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors
[Image: see text] d-myo-Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are Ca(2+) channels activated by the intracellular messenger inositol 1,4,5-trisphosphate (IP(3), 1). The glyconucleotide adenophostin A (AdA, 2) is a potent agonist of IP(3)Rs. A recent synthesis of d-chiro-inositol adenophost...
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| Veröffentlicht in: | ACS Omega |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2020
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659177/ https://ncbi.nlm.nih.gov/pubmed/33195933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04145 |
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