Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain

BACKGROUND: Despite advances in our understanding of basic mechanisms driving post-surgical pain, treating incision-induced pain remains a major clinical challenge. Moreover, surgery has been implicated as a major cause of chronic pain conditions. Hence, more efficacious treatments are needed to inh...

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Autores principales: Tillu, Dipti V, Melemedjian, Ohannes K, Asiedu, Marina N, Qu, Ning, De Felice, Milena, Dussor, Gregory, Price, Theodore J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284441/
https://ncbi.nlm.nih.gov/pubmed/22269797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-5
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