Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP

Multiple intergenic single-nucleotide polymorphisms (SNPs) near hedgehog interacting protein (HHIP) on chromosome 4q31 have been strongly associated with pulmonary function levels and moderate-to-severe chronic obstructive pulmonary disease (COPD). However, whether the effects of variants in this re...

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Main Authors: Zhou, Xiaobo, Baron, Rebecca M., Hardin, Megan, Cho, Michael H., Zielinski, Jan, Hawrylkiewicz, Iwona, Sliwinski, Pawel, Hersh, Craig P., Mancini, John D., Lu, Ke, Thibault, Derek, Donahue, Amy L., Klanderman, Barbara J., Rosner, Bernard, Raby, Benjamin A., Lu, Quan, Geldart, Adriana M., Layne, Matthew D., Perrella, Mark A., Weiss, Scott T., Choi, Augustine M.K., Silverman, Edwin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284120/
https://ncbi.nlm.nih.gov/pubmed/22140090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr569
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