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Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP

Multiple intergenic single-nucleotide polymorphisms (SNPs) near hedgehog interacting protein (HHIP) on chromosome 4q31 have been strongly associated with pulmonary function levels and moderate-to-severe chronic obstructive pulmonary disease (COPD). However, whether the effects of variants in this re...

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Main Authors: Zhou, Xiaobo, Baron, Rebecca M., Hardin, Megan, Cho, Michael H., Zielinski, Jan, Hawrylkiewicz, Iwona, Sliwinski, Pawel, Hersh, Craig P., Mancini, John D., Lu, Ke, Thibault, Derek, Donahue, Amy L., Klanderman, Barbara J., Rosner, Bernard, Raby, Benjamin A., Lu, Quan, Geldart, Adriana M., Layne, Matthew D., Perrella, Mark A., Weiss, Scott T., Choi, Augustine M.K., Silverman, Edwin K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284120/
https://ncbi.nlm.nih.gov/pubmed/22140090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr569
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