Hhip haploinsufficiency sensitizes mice to age-related emphysema

Genetic variants in Hedgehog interacting protein (HHIP) have consistently been associated with the susceptibility to develop chronic obstructive pulmonary disease and pulmonary function levels, including the forced expiratory volume in 1 s (FEV(1)), in general population samples by genome-wide assoc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lao, Taotao, Jiang, Zhiqiang, Yun, Jeong, Qiu, Weiliang, Guo, Feng, Huang, Chunfang, Mancini, John Dominic, Gupta, Kushagra, Laucho-Contreras, Maria E., Naing, Zun Zar Chi, Zhang, Li, Perrella, Mark A., Owen, Caroline A., Silverman, Edwin K., Zhou, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987811/
https://ncbi.nlm.nih.gov/pubmed/27444019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602342113
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