Hhip haploinsufficiency sensitizes mice to age-related emphysema

Genetic variants in Hedgehog interacting protein (HHIP) have consistently been associated with the susceptibility to develop chronic obstructive pulmonary disease and pulmonary function levels, including the forced expiratory volume in 1 s (FEV(1)), in general population samples by genome-wide assoc...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lao, Taotao, Jiang, Zhiqiang, Yun, Jeong, Qiu, Weiliang, Guo, Feng, Huang, Chunfang, Mancini, John Dominic, Gupta, Kushagra, Laucho-Contreras, Maria E., Naing, Zun Zar Chi, Zhang, Li, Perrella, Mark A., Owen, Caroline A., Silverman, Edwin K., Zhou, Xiaobo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987811/
https://ncbi.nlm.nih.gov/pubmed/27444019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602342113
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